I'm on the first step in the xhmm pipeline, which involves running my .bam files into DepthOfCoverage. I have 13 bam files (1 for each exome) and it ran out of memory (8gb) per core (10 cores) after 40 hours. Is it neccesary to pass all the .bam files together into DepthOfCoverage for xhmm? Would it significantly reduce time if I passed each bam file individually?
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